INDICATIONS FOR BIOCHEMICAL STUDIES OF BIOMATERIAL

 

• Patient’s general well-being complaints;
• Diagnostics of abdominal cavity and thyroid gland pathologies and dysfunctions.

 

OUR LABORATORY PERFORMS:

 

Biochemical blood tests

Tests for metabolites of glucose and carbohydrate metabolism

• Glucose tests
• Glycated hemoglobin test

Protein assay

• Total protein test
• Albumin test
• Protein electrophoresis (albumin, α1-globulins, α2-globulins, β-globulins, γ-globulins)

Small-molecule nitrogenous matter

• Urea
• Creatinine
• Uric acid

Kidney function assessment (evaluation of glomerular filtration rate)

• Cystatin C
• Cystatin glomerular filtration rate estimation
• Creatinine glomerular filtration rate estimation

Pigment exchange

• Total bilirubin
• Direct (conjugated) bilirubin

Lipid exchange

• Cholesterol
• High-density lipoproteins (НDL)
• Low-density lipoproteins (LDL)
• Triglycerids
• Apolipoprotein А1 (АРО-А1)
• Apolipoprotein В (АРО-В)
• Lipoprotein (A)
• Lipoprotein electrophoresis (α-lipoproteins, pre-β-lipoproteins, β-lipoproteins, chylomicrons)

Enzymes

• AspAt (aspartate aminotransferase)
• AlAt (alanine aminotransferase)
• Total alpha-amylase
• Pancreatic amylase
• Lipase
• Gamma-glutamyl transpeptidase (GGTP)
• Alkaline phosphatase
• Creatine kinase
• Creatine kinase-MB (activity)
• Creatine kinase-MB (mass)
• Lactate dehydrogenase (LDH)

Inorganic substances (micronutrients)

• Potassium, Sodium, Chlorine
• Inorganic phosphorus
• Total calcium
• Ionized calcium
• Magensium
• Serum iron

Specific proteins

• Proteins involved in iron metabolism
• Transferrin
• Ferritin
• Immunoglobulins A, M, G
• Cardiospecific proteins and cardiovascular disorder risk markers
• Myoglobin
• Creatine kinase
• Creatine kinase-MB (activity)
• Creatine kinase-MB (mass)
• Lactate dehydrogenase (LDH)
• proBNP (brain natriuretic peptide)
• High sensitivity troponin

Acute phase proteins and inflammation markers

• C-reactive protein
• Complement factor С3
• Complement factor С4
• Antistreptolysin O
• Rheumatoid factor
• Procalcitonin
• Presepsin
• Interleukin-6
• Haptoglobin

Homocysteine

Homocysteine is a sulfur-containing amino acid in blood plasma. High levels of homocysteine increase the risk of heart disease, stroke, Alzheimer's disease, and osteoporosis.

Rehberg Test

(autogenous creatinine clearance)

·         biochemical assay of kidney function, creatinine glomerular filtration rate estimation

Urine biochemistry

• Urine glucose measurement
• Urine protein measurement
• Urine albumin measurement
• Urine urea measurement
• Urine creatinine measurement
• Urine amylase measurement
• Urine uric acid measurement
• Urine calcium measurement
• Urine phosphorus measurement
• Urine pancreatic amylase measurement
• Urine potassium measurement
• Urine sodium measurement
• Urine magnesium measurement

Biochemical studies of synovial fluid

Synovial fluid is one of the main components of each joint, which determines its morphofunctional state. Synovial fluid reflects the processes occurring in the cartilage and synovial membrane. That is why the laboratory study of synovial fluid is of fundamental importance in the diagnosis of joint diseases. In some cases, this is the first, and sometimes the only necessary diagnostic test. Biochemical examination of synovial fluid should always be combined with evaluation of physicochemical properties and microscopy Biochemical parameters for evaluation of synovial fluid:

• Determination of total protein concentration
• Determination of albumin concentration
• Determination of albumin/globulin ratio
• Determination of glucose concentration
• Determination of rheumatoid factor concentration
• Determination of uric acid concentration
• Determination of LDH concentration
• Determination of CRP concentration

Biochemical study of effusion fluids

The study of effusion fluids is currently of high importance in the diagnosis of pathological conditions. The data obtained from this study allow the clinician to obtain information about the pathogenesis of effusion formation and correctly organize therapeutic measures. Biochemical examination of effusion fluids should always be combined with an assessment of the physicochemical properties and microscopy. Simultaneously with the collection of effusion fluid, venous blood is taken from the patient for subsequent biochemical studies of analytes and calculation of indices.

Biochemical parameters for assessing effusion fluids

• Determination of total protein concentration
• Protein-Liquid/Protein-Whey
• Determination of albumin concentration
• Determination of albumin/globulin ratio
• Determination of glucose concentration
• Determination of cholesterol concentration
• Determination of triglyceride concentration
• Determination of LDH concentration
• Determination of the LDH-liquid/LDH-serum ratio
• Determination of α-amylase concentration

Biochemical studies are performed using:

• Immunobiology and photometry testing station Cobas 6000 made by Roche Diagnostics GmbH., Germany.
• Immunochemical electrochemiluminescence analyzer Cobas e 411 made by Roche Diagnostics GmbH., Germany.
• AU480 analyzer featuring an ISE unit, made by Beckman Coulter Inc., Japan
• Automatic clinical electrophoresis system INTERLAB G 26 made by Interlab S.r.l., Italy
• Immunological electrochemiluminescence analyzer PATHFAST made by LSI Medience Corporation, Japan
• Glucose and lactate measuring analyzer BIOSEN C-line Clinic made by EKF-diagnostic GmbH, Germany
• Hemoglobin testing system D-10 complete with accessories, made by Bio-Rad Laboratories, USA
• Automated glycated hemoglobin analyzer Adams А1 с НА-8180 М made by ARKRAY Factory, Inc, Japan
• Blood gas analyzer ABL800FLEX manufactured by Radiometr Medical ApS, Denmark

PREPARATION FOR BLOOD ANALYSIS

Rules for preparing a patient for blood donation for biochemical research

Rules for preparing the patient for the Reberg test

HOW TO TAKE A BLOOD TEST

1. At the reception, conclude an agreement for the provision of paid services (if you have a referral from a doctor, show it to the medical registrar)
2. Pay the invoice at the cash desk of the RCMC or via ЕРИП (SSIS: Single Settlement and Information Space)
3. Get tested.

Test material is accepted according to schedule: Friday through Monday, from 7:30 till 11:00, Saturday from 9:00 to 11:00 (on Saturday, tests are accepted by appointment through the Contact Center). Test results are made available to the physician and the patient at 15:00 on the same day.